Cancer Research Replication Problem

The Institute of Medicine estimates that only 4 percent of treatments and tests are backed up by strong scientific evidence: more than half have very weak evidence or none


An eight year project that tried to reproduce the results of key cancer biology studies has finally concluded and its findings suggest that similar to research in the social sciences, cancer research has a replication problem. The effort to replicate nearly 200 preclinical cancer experiments that generated buzz from 2010 to 2012 found that only about a quarter could be reproduced. 1 Researchers with the Reproducibility Project Cancer Biology aimed to replicate 193 experiments from 53 top cancer papers published from 2010 to 2012. But only a quarter of those experiments were able to be reproduced. 2
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