New treatment offers hope for multiple myeloma and lymphoma

Karyopharm of Israel and Massachusetts gets FDA approval for XPOVIO, the first drug aimed to help natural tumor-suppressing proteins do their job.

By ISRAEL21c —— Bio and Archives--October 20, 2019

Health and Medicine | Comments | Back To Full Article

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Cancer is a devious adversary. It figures out all kinds of ways to hide from the body’s detection systems and grow unchecked until it’s too late to stop them. One of cancer’s most cunning methods of evading the immune system is to increase the frequency of a kind of cellular “train” – a protein called XPO1 – that makes regular back-and-forth trips in and out of the nucleus of a cell. The XPO1 protein’s job is to shuttle other proteins to the right stops on the line.

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