A low level of vitamin D in blood plasma appears to be an independent risk factor for Covid-19 infection and hospitalization, say scientists from Israeli HMO Leumit Health Services and the Azrieli Faculty of Medicine of Bar-Ilan University.
The researchers came to their conclusion using real-world data and an Israeli cohort of 782 Covid-19 positive patients and 7,025 Covid-19 negative patients.
Reduced risk of acute respiratory tract infection following vitamin D supplementation
“The main finding of our study was the significant association of low plasma vitamin D level with the likelihood of Covid-19 infection among patients who were tested for Covid-19, even after adjustment for age, gender, socio-economic status and chronic, mental and physical disorders,” said Dr. Eugene Merzon, head of Leumit’s Department of Managed Care.
“Furthermore, low vitamin D level was associated with the risk of hospitalization due to Covid-19 infection, although this association wasn’t significant after adjustment for other factors,” he added.
The scientists’ research follows a few worldwide studies that have shown the pronounced impact of vitamin D metabolites on the immune system response and on the development of Covid-19 infection by the novel SARS CoV-2 coronavirus.
“Our finding is in agreement with the results of previous studies in the field. Reduced risk of acute respiratory tract infection following vitamin D supplementation has been reported,” said Dr. Ilan Green, head of Leumit’s Research Institute.
As for the amount of vitamin D required, Merzon says it should be “personalized and take into account patients’ age, gender, race and ethnicity, nutritional status and health condition.”-- More...
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