This is not a Messianic cry of frustration or despair.
The above question is a quaint reaction to the non-stop rejection of conservative Trump supporters for Ted Cruz.
They despise him for his initial support for the H-1b Visa program. When he acknowledged the abuses and changed his mind on the program, pro-enforcement factions still give Cruz no respite.
When he had advocated for the TPA authority to facilitate trade deals with other countries, he argued for these reforms in order to help American companies and workers. As criticism rose against the program, Cruz would vote against the TPP accords to follow.