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Pfizer abruptly stopped development of its newest heart medicine in 2006, when clinical trials showed it was increasing patients’ risk of death.

Lessons from an $800-million drug flop may lead to a new genre of anti-cholesterol medicines


Chemical & Engineering News Mindful of lessons from a failed heart drug that cost $800 million to develop, drug companies are taking another shot at new medications that boost levels of so-called “good cholesterol,” which removes cholesterol from the body. A report on how three new versions of medications in the same family as the failed torcetrapib appears in the current edition of Chemical & Engineering News, the news magazine of the American Chemical Society, the world’s largest scientific society.
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