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Replacing defective genes that cause gradual hearing loss in mice is successful and could lead to treatment for human babies with similar mutations

Scientists develop new gene therapy for deafness


Delivering healthy genetic material into the inner ear cells of mice with a genetic defect that causes deafness enables the cells to function normally, according to a new study from Tel Aviv University (TAU). The novel treatment prevented the gradual deterioration of hearing in these mice. It could lead to a breakthrough in treating children born with various mutations that eventually cause deafness. The study, led by Prof. Karen Avraham of the Department of Human Molecular Genetics and Biochemistry at TAU’s Sackler Faculty of Medicine and Sagol School of Neuroscience, was published in EMBO Molecular Medicine on December 22.
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