Shedding light on the limits of the expanded genetic code

Light can cause synthetic nucleosides to damage cells


In 2014, scientists made a huge news splash when they reported the ability to grow bacteria with an expanded genetic code. Critics feared the rise of unnatural creatures; others appreciated the therapeutic potential of the development. Now researchers have found that the expanded code might have an unforeseen limitation. A study in the Journal of the American Chemical Society reports that these novel components can damage cells when they are exposed to light.
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