Oren Yifa, left, and Prof. Eldad Tzahor at the Weizmann Institute of Science in Rehovot, IsraelA non-toxic blue dye commonly used in biology labs helps repair damaged heart tissue in mice, say researchers at the Weizmann Institute of Science in Israel.
As described in the Journal of Clinical Investigation Insight, a dye molecule called Chicago Sky Blue reduced scar size and improved heart function of adult mice following induced myocardial infarction (heart attack).
Once damaged, heart muscle cells (cardiomyocytes) can never regenerate. But when research student Oren Yifa and his team injected Chicago Sky Blue into the post-heart attack mice in the molecular cell biology lab of Prof. Eldad Tzahor, the mice’s heart function improved.
Their research suggests that the dye works in two ways: reducing inflammation and inhibiting the actions of a certain enzyme overproduced in heart disease.
