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A study with pepper plants sheds light on how antibiotics and related molecules can end up in food

Pepper plant sops up personal care product antibiotic


By —— Bio and Archives--April 23, 2018

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Pepper plant sops up personal care product antibiotic
It sometimes can be hard to find toothpastes, soaps and other toiletries without antibiotics. Their popularity has caused an increase in environmental levels of antimicrobial substances, such as triclocarban (TCC), which end up in the water and soil used to grow crops. Scientists report in the ACS’ Journal of Agricultural and Food Chemistry that TCC and related molecules can end up in food, with potentially negative health effects.

The U.S. Food and Drug Administration recently banned TCC from soaps because of questions about its safety and efficacy. Yet, TCC remains in many other products. It’s also found in high concentrations in treated wastewater that is sometimes used to irrigate crops. The impact of TCC on human health remains unclear, but it may act as an endocrine disruptor. One obstacle to better understanding the risks of environmental TCC exposure is uncertainty about how much of it ends up in plants, and how plants metabolize the substance. So, Dawn Reinhold and colleagues undertook a study with jalapeno peppers to address this knowledge gap.

To track the antibiotic’s journey from water to pepper, the researchers labeled TCC with radioactive carbon (C14). They grew the pepper plants hydroponically and, after 12 weeks, sampled the C14 content in the roots, stems, leaves and fruit. While the pepper fruit itself had relatively low levels of TCC, it contained a hefty portion of C14 in molecules that started out as TCC but then were converted to other molecules by the plant. According to the researchers, this finding indicated that the plant was metabolizing the antibiotic, and the health impact of these metabolites would need to be taken into account to fully assess the safety of TCC consumption.

The authors acknowledge funding the National Institute of Food and Agriculture within the U.S. Department of Agriculture, the National Science Foundation and the Vietnam Education Foundation.

Transformation, Conjugation, and Sequestration Following the Uptake of Triclocarban by Jalapeno Pepper Plants


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American Chemical Society, ACS is a congressionally chartered independent membership organization which represents professionals at all degree levels and in all fields of chemistry and sciences that involve chemistry.


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