In recent months, the parliaments in Ireland and in Chile took unprecedented measures that place severe limitations on economic trade with the settlements in the West Bank. Although at this stage these decisions are not binding and their direct impact is limited, their acceptance reflects the illegitimacy many international actors attribute to the settlements and their willingness to take concrete action against them. These decisions, alongside the possibility that the UN Human Rights Council will soon publish a blacklist of Israeli and international companies active in the settlements, may lead to additional steps that could impact negatively on Israel’s global public and political standing, its political freedom of action, and even its economy. Accordingly, proactive steps should be taken to lessen the impact of decisions already taken and to prevent the adoption of additional such measures.