President Obama’s upcoming visit to Israel, along with the formation of a new Israeli government, is an opportunity for the United States and Israel to formulate a joint strategy toward the challenges of the Middle East. The two countries view the main trends in the region with concern: Iranian efforts to acquire military nuclear capability continue unabated, and in Syria, the struggle between the Assad regime and opposition forces continues, joined by the concern that strategic weapons could end up in the hands of extremist elements. In addition, there has been no progress on the Palestinian issue, nor has a solution been found to the “crisis of honor” between Israel and Turkey. Political Islam continues to intensify, and the Muslim Brotherhood has tightened its hold in Egypt.