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Chemotherapy could someday have fewer side effects if loaded into a "protocell" nanoparticle that specifically burrows into the deepest tumor regions

Bridging tumor moats with potent drug delivery particles


Bridging tumor moats with potent drug delivery particles Despite herculean efforts, cancer remains a formidable disease, with each malignant subtype responding differently to therapeutics. One hurdle specific to treating solid tumors is a protective layer called an extracellular matrix that can prevent chemotherapeutic agents from penetrating the tumor's core. Scientists now report results in ACS' Chemistry of Materials showing that, by cloaking anti-cancer drugs in a specially designed particle, they could target and destroy tumor cells deep inside a malignant mass in vitro.
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